In the meantime, to ensure continued support, we are displaying the site without styles and Java Script.Given the importance of Africa to studies of human origins and disease susceptibility, detailed characterization of African genetic diversity is needed.
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2 and Supplementary Note 5), consistent with linguistic assimilation of click consonants among these populations.
We examined highly differentiated SNPs between European and African populations, as well as among African populations to gain insights into loci that may have undergone selection in response to local adaptive forces (Supplementary Methods).
Finally, we present an efficient genotype array design capturing common genetic variation in Africa.
Globally, human populations show structured genetic diversity as a result of geographical dispersion, selection and drift.
K = 6 and K = 18 were the most likely clusters on ADMIXTURE analysis.
ADMIXTURE analysis suggests substructure between North, East, West and South Africa. You are using a browser version with limited support for CSS.To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer).The African Genome Variation Project provides a resource with which to design, implement and interpret genomic studies in sub-Saharan Africa and worldwide.The African Genome Variation Project represents dense genotypes from 1,481 individuals and whole-genome sequences from 320 individuals across sub-Saharan Africa.Differentiation among the Niger-Congo language groups—the predominant linguistic grouping across Africa was noted to be modest (mean pairwise F.