Sheldon appoints himself as the captain of the guys' paintball team.
This upsets him, creating a standoff between himself and his mother.
When he talks about his mother's behavior to Amy, she counsels him that while he is a genius, his emotional reactions to his mother ignoring him are no different from that of any other human being, and that the less intelligent might be able to handle their emotions better by not over thinking them.
Raj has feelings for Penny talks to her about the recent events.
Penny feels that this has damaged her relationship with the guys permanently and decides to move back to Nebraska, as she has not had any worthwhile acting jobs since moving to Pasadena.
Howard is ecstatic to learn that he will be traveling to the International Space Station as a payload specialist to assist in the implementation of a deep space telescope designed by his engineering team.
Meanwhile, while Sheldon and Leonard are at the comic book store, Wil Wheaton shows up and invites them to a party at his house that Friday.
Howard asks her to stay with him and his mother for the weekend as a "trial", to which she agrees.
Penny sets up Raj on a date with her deaf friend Emily, for whom his selective mutism is no longer an issue.
The season finale depicts Howard Wolowitz traveling to the International Space Station (ISS) on board a Soyuz rocket.